Anticardiolipin and anti-ß2-glycoprotein 1 in Omani patients with anti-phospholipid syndrome

Studies have shown that plasma glycoprotein with phospholipid-binding property is required for ACA., to bind to cardiolipin that has been coated onto plastic plates. This cofactor has been identified as β2-glycoprotein 1 (β2GPl). Later, it was found that β2GPl is indeed the antigen to which many ACA patients are actually binding and the phospholipid merely serves to link the β2GPl to the solid phase.